| Primary information |
|---|
| ID | antitb_1607 |
| Peptide Name | TP-5 |
| Sequence | RKDVY |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 4 |
| Chirality | L |
| Nature | Cationic |
| Source | Synthetic |
| Origin | NA |
| Species | Mycobacterium smegmatis |
| Strain | Mycobacterium smegmatis RIF-susceptible |
| Inhibition Concentartion | MIC = > 1000mg/L |
| In vitro/In vivo | in vitro |
| Cell Line | RAW 264.7 mouse macrophage |
| Inhibition Concentartion | NA |
| Cytotoxicity | HC50= > 2000 mg/L on Human RBC |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | Stimulate TNF-α production |
| Mechanism of Action | Disrupt the mycobacterial membrane |
| Target | NA |
| Combination Therapy | NA |
| Other Activities | NA |
| Pubmed ID | 24411680 |
| Year of Publication | 2014 |
| 3-D Structure |  View in Jmol or Download Structure |