| Primary information |
|---|
| ID | antitb_1555 |
| Peptide Name | Pk34 |
| Sequence | PRVIETKVHGREVTGLARNVSEENVDRLAKRWIK |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 34 |
| Chirality | L |
| Nature | Cationic |
| Source | Mycobacteriophage derived |
| Origin | Derived from mycobacteriophage |
| Species | Mycobacterium tuberculosis |
| Strain | Mycobacterium tuberculosis H37Rv |
| Inhibition Concentartion | IC50= 50 μg/ml |
| In vitro/In vivo | in vitro |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| Cytotoxicity | Macrophage like J774A.1 cell line |
| In vivo Model | BALB/C mice |
| Lethal Dose | 20mg/Kg |
| Immune Response | Increase production of cytokine like IFN-γ,TNF-α,IL-12,MCp-1, IL-10, IL-6 |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other Activities | Bactericidal against E.coli, pseudomonas, S.aureus, Bacillus subtilis |
| Pubmed ID | 25613372 |
| Year of Publication | 2015 |
| 3-D Structure |  View in Jmol or Download Structure |