| Primary information |
|---|
| ID | antitb_1502 |
| Peptide Name | Cyclomarin A |
| Sequence | not available |
| N-terminal Modification | NA |
| C-terminal Modification | NA |
| Chemical Modification | NA |
| Linear/ Cyclic | Branched cyclic |
| Length | 0 |
| Chirality | D |
| Nature | Cationic |
| Source | Natural |
| Origin | Derived from Streptomyces species |
| Species | Mycobacterium tuberculosis |
| Strain | Mycobacterium tuberculosis H37Rv |
| Inhibition Concentartion | IC50= 0.3mg/ml |
| In vitro/In vivo | in vitro |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | |
| Mechanism of Action | Change the clp1subunit of casinolytic protease by allosteric binding |
| Target | NA |
| Combination Therapy | NA |
| Other Activities | Antibacterial against E.coli, S.aureus, bacillus, pseudomonas |
| Pubmed ID | 25681127 |
| Year of Publication | 2015 |
| 3-D Structure | NA |