| Primary information |
|---|
| ID | antitb_1478 |
| Peptide Name | Lariatin A |
| Sequence | GSQLVYRWVGHSNVIKGP |
| N-terminal Modification | NA |
| C-terminal Modification | NA |
| Chemical Modification | Alpha carbon of glutamine form amide bond with first glycine and gamma carbon of glutamine involved in side chain formation |
| Linear/ Cyclic | Cyclic |
| Length | 18 |
| Chirality | D |
| Nature | Cationic |
| Source | Natural |
| Origin | Derived from Rhodococcusjostii K01â€B0171 |
| Species | Mycobacterium tuberculosis |
| Strain | Mycobacterium tuberculosis Rv |
| Inhibition Concentartion | MIC = 0.39 mg/L |
| In vitro/In vivo | in vitro |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | Inhibit cell wall biosynthesis |
| Target | NA |
| Combination Therapy | NA |
| Other Activities | NA |
| Pubmed ID | 25681127 |
| Year of Publication | 2015 |
| 3-D Structure | NA |