| Primary information |
|---|
| ID | antitb_1477 |
| Peptide Name | Nocathiacins |
| Sequence | not available |
| N-terminal Modification | NA |
| C-terminal Modification | NA |
| Chemical Modification | NA |
| Linear/ Cyclic | Branched cyclic |
| Length | 0 |
| Chirality | NA |
| Nature | Cationic |
| Source | Natural |
| Origin | Derived from Nocardia species |
| Species | Mycobacterium pneumoniae |
| Strain | Mycobacterium pneumoniae |
| Inhibition Concentartion | MIC = ≤0.008 mg/ml |
| In vitro/In vivo | in vitro |
| Cell Line | McCoy cell lines |
| Inhibition Concentartion | NA |
| Cytotoxicity | 0.25 μg/ml |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | Bind to the 23S rRNA of the 50S ribosomal subunit and inhibit translation |
| Target | 23srRNA subunit of bacteria |
| Combination Therapy | NA |
| Other Activities | NA |
| Pubmed ID | 25681127 |
| Year of Publication | 2015 |
| 3-D Structure | NA |