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Detailed description page of AntiTbPdb

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antitb_1444 details
Primary information
IDantitb_1444
Peptide NameA2-Ag85B
SequenceFIYAGSLSA
N-terminal ModificationFree
C-terminal ModificationFree
Chemical ModificationNone
Linear/ CyclicLinear
Length9
ChiralityL
NatureNA
SourceProtein derived
OriginMTB derived protein Ag85B
SpeciesMycobacterium tuberculosis
StrainMycobacterium tuberculosis Rv
Inhibition ConcentartionNA
In vitro/In vivoNA
Cell LineNA
Inhibition ConcentartionNA
CytotoxicityNA
In vivo ModelNA
Lethal DoseNA
Immune ResponseIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatment
Mechanism of ActionDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy.
TargetCD8+ T-cell
Combination TherapyNA
Other ActivitiesNA
Pubmed ID25809751
Year of Publication2104
3-D Structure View in Jmol or Download Structure