Primary information |
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ID | antitb_1436 |
Peptide Name | Tetrahydroviomycin |
Sequence | H2N-CH-CH-CH-CH-R1-CH-NH2-Ch-CO-Nh-C-CO-NH-CH2OH-CO-NH-CH(CH2OH)-CO-NH-R2-CO-R3-HN-CH |
N-terminal Modification | Free |
C-terminal Modification | Free |
Chemical Modification | R1 = H, r2 = >CH-OH, R3=Tbd(Tuberactidine) |
Linear/ Cyclic | NA |
Length | 38 |
Chirality | NA |
Nature | NA |
Source | NA |
Origin | NA |
Species | Mycobacterium tuberculosis |
Strain | Mycobacterium tuberculosis 607 |
Inhibition Concentartion | MIC = 3.1 μg/ml |
In vitro/In vivo | in vitro |
Cell Line | NA |
Inhibition Concentartion | NA |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other Activities | Antibacterial against Bacillus subtilis, Pseudomonas aeruginosa, proteus vulgaris, satphylococus aureous |
Pubmed ID | 197067 |
Year of Publication | 1977 |
3-D Structure | NA |