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Detailed description page of AntiTbPdb

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antitb_1388 details
Primary information
IDantitb_1388
Peptide NameHepcidin
SequenceDTHFPICIFCCGCCHRSKCGMCCKT
N-terminal ModificationFree
C-terminal ModificationFree
Chemical ModificationDisulphide linkage between cys7-23, cys10-13, cys11-19,cys14-22
Linear/ CyclicCyclic
Length25
ChiralityL
NatureCationic
SourceNatural
OriginHuman alveolar type 2 epithilium
SpeciesMycobacterium tuberculosis
StrainMycobacterium H37Rv
Inhibition ConcentartionNA
In vitro/In vivoin vivo
Cell LineA549 cell line
Inhibition ConcentartionNA
CytotoxicityNo cytotoxicity
In vivo ModelBALB/C
Lethal DoseNA
Immune ResponseIncreased production of TNF-α, IL-1α
Mechanism of ActionNA
TargetMycobacterium tuberculosis + IFN-Î¥
Combination Therapy
Other Activitiesantimicrobial
Pubmed ID21482189
Year of Publication2011
3-D StructureNA