| Primary information |
|---|
| ID | antitb_1388 |
| Peptide Name | Hepcidin |
| Sequence | DTHFPICIFCCGCCHRSKCGMCCKT |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Chemical Modification | Disulphide linkage between cys7-23, cys10-13, cys11-19,cys14-22 |
| Linear/ Cyclic | Cyclic |
| Length | 25 |
| Chirality | L |
| Nature | Cationic |
| Source | Natural |
| Origin | Human alveolar type 2 epithilium |
| Species | Mycobacterium tuberculosis |
| Strain | Mycobacterium H37Rv |
| Inhibition Concentartion | NA |
| In vitro/In vivo | in vivo |
| Cell Line | A549 cell line |
| Inhibition Concentartion | NA |
| Cytotoxicity | No cytotoxicity |
| In vivo Model | BALB/C |
| Lethal Dose | NA |
| Immune Response | Increased production of TNF-α, IL-1α |
| Mechanism of Action | NA |
| Target | Mycobacterium tuberculosis + IFN-Î¥ |
| Combination Therapy | |
| Other Activities | antimicrobial |
| Pubmed ID | 21482189 |
| Year of Publication | 2011 |
| 3-D Structure | NA |