Primary information |
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ID | antitb_1388 |
Peptide Name | Hepcidin |
Sequence | DTHFPICIFCCGCCHRSKCGMCCKT |
N-terminal Modification | Free |
C-terminal Modification | Free |
Chemical Modification | Disulphide linkage between cys7-23, cys10-13, cys11-19,cys14-22 |
Linear/ Cyclic | Cyclic |
Length | 25 |
Chirality | L |
Nature | Cationic |
Source | Natural |
Origin | Human alveolar type 2 epithilium |
Species | Mycobacterium tuberculosis |
Strain | Mycobacterium H37Rv |
Inhibition Concentartion | NA |
In vitro/In vivo | in vivo |
Cell Line | A549 cell line |
Inhibition Concentartion | NA |
Cytotoxicity | No cytotoxicity |
In vivo Model | BALB/C |
Lethal Dose | NA |
Immune Response | Increased production of TNF-α, IL-1α |
Mechanism of Action | NA |
Target | Mycobacterium tuberculosis + IFN-Î¥ |
Combination Therapy | |
Other Activities | antimicrobial |
Pubmed ID | 21482189 |
Year of Publication | 2011 |
3-D Structure | NA |