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Detailed description page of AntiTbPdb

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antitb_1354 details
Primary information
IDantitb_1354
Peptide NameNk-lysin
SequenceNEDTVTQAASRVCDKMKILRGVCKKIMRTFLRRISKD
N-terminal ModificationFree
C-terminal ModificationFree
Chemical ModificationInternal disuphide bond 13 -23
Linear/ CyclicCyclic
Length37
ChiralityL
NatureNA
SourceNatural
OriginPig cytolytic lymphocytes
SpeciesMycobacterium tuberculosis
StrainMycobacterium tuberculosis H37Rv ATCC 25618
Inhibition ConcentartionIC90 = 30 μM
In vitro/In vivoIn vitro
Cell LineHuman erythroleukaemia cell line K562
Inhibition ConcentartionNA
Cytotoxicity30 % cytolytic activity in range of 3 -7 μM peptide concentration
In vivo ModelNA
Lethal DoseNA
Immune ResponseNA
Mechanism of ActionNA
TargetNA
Combination TherapyNA
Other ActivitiesAntibacterial against bacillus megaterium, E.coli, P.aeuroginosaand S.aureus
Pubmed ID10585872
Year of Publication1999
3-D StructureNA