| Primary information |
|---|
| ID | antitb_1336 |
| Peptide Name | Dihydromycoplanecin A |
| Sequence | R-N(CH3)-CH(CH-CH3-CH3)-CO-N(CH-C-CH2-CH3-C-CH)-CO-N(CH3)-CH-C)-NH-CH(CH2-CH-CH3-CH3)-CO-N-CH-C-CH3_C-CH)-CONH-CH(CH2-CH2-CH-CH3-CH3)-Co-N-CH3-Ch-CH(CH3-CH3)-Co-N-(CH-C-Ch)-Co-N(CH3)-CH(CH2-CH-CH3-CH3)-CO-NH-CH2-CO-O-CH(CH3) |
| N-terminal Modification | Propanol is attached |
| C-terminal Modification | Free |
| Chemical Modification | R =CH3-CH2-CH(OH)-CO |
| Linear/ Cyclic | Cyclic |
| Length | 21 |
| Chirality | Mix |
| Nature | NA |
| Source | Natural |
| Origin | Aspergillus awajinensis |
| Species | Mycobacterium intracellulare |
| Strain | Mycobacterium intracellulare |
| Inhibition Concentartion | IC50 = 1.56 μg/mL (50%) |
| In vitro/In vivo | Both |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| Cytotoxicity | NA |
| In vivo Model | ICR/JCL male mice and male beagle dogs |
| Lethal Dose | 11 mg/kg for mice and 50mg/kg for dog |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other Activities | NA |
| Pubmed ID | 3348603 |
| Year of Publication | 1988 |
| 3-D Structure | NA |