| Primary information |
|---|
| ID | antitb_1302 |
| Peptide Name | Ubiquitin-derived peptide (Ub2) |
| Sequence | STLHLVLRLRGG |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 12 |
| Chirality | L |
| Nature | Cationic |
| Source | Natural |
| Origin | Ubiquitin derived |
| Species | Mycobacterium smegmatis |
| Strain | M. smegmatis mc2 155 |
| Inhibition Concentartion | 1.5 fold reduction in bacterial colony as compared to control at 50 μM of peptide |
| In vitro/In vivo | In vitro |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | Pore formation in Mycobacterial membrane |
| Target | mspA gene which form porins in membrane, peptide increase the expression of this gene |
| Combination Therapy | NA |
| Other Activities | NA |
| Pubmed ID | 19682257 |
| Year of Publication | 2009 |
| 3-D Structure |  View in Jmol or Download Structure |