| Primary information |
|---|
| ID | antitb_1297 |
| Peptide Name | Trichoderins A1 |
| Sequence | (MDA)-P-(AMOD)-(Aib)-(Aib)-I-V-(Aib)-(Aib)-(AMAE) |
| N-terminal Modification | Addition of MDA = 2-methyl decanoic acid. |
| C-terminal Modification | Addition of AMAE = 2-[(20-aminopropyl) methylamino] ethanol. |
| Chemical Modification | AMOD = 2-amino-4-methy1-8-oxodec-6-enoic acid, Aib = a-amino- isobutyric acid, |
| Linear/ Cyclic | Linear |
| Length | 8 |
| Chirality | L |
| Nature | NA |
| Source | Natural |
| Origin | Isolated from a culture of marine sponge derived fungus of Trichoderma sp. |
| Species | Mycobacterium bovis |
| Strain | Mycobacterium bovis BCG |
| Inhibition Concentartion | MIC = 0.16 μg/mL |
| In vitro/In vivo | In vitro |
| Cell Line | None |
| Inhibition Concentartion | NA |
| Cytotoxicity | NA |
| In vivo Model | None |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | None |
| Other Activities | None |
| Pubmed ID | 20483615 |
| Year of Publication | 2010 |
| 3-D Structure | NA |