Primary information |
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ID | antitb_1257 |
Peptide Name | Eosinophil Cationic Protein (RNase 3) |
Sequence | RPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNN |
N-terminal Modification | Free |
C-terminal Modification | Free |
Chemical Modification | Disulphide linkage |
Linear/ Cyclic | Cyclic |
Length | 70 |
Chirality | L |
Nature | Cationic |
Source | Natural |
Origin | Secreted by eosinophil secondary granules |
Species | Mycobacterium vaccae |
Strain | Mycobacterium vaccae strain (ATCC 15483) |
Inhibition Concentartion | IC50 = 11.6 ± 0.2 μM |
In vitro/In vivo | In vitro |
Cell Line | None |
Inhibition Concentartion | NA |
Cytotoxicity | NA |
In vivo Model | None |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | Membrane depolarization and permeabilization |
Target | Cell envelope |
Combination Therapy | None |
Other Activities | Antibacterial and Antiparasitic |
Pubmed ID | 23716047 |
Year of Publication | 2013 |
3-D Structure | NA |