| Primary information |
|---|
| ID | antitb_1246 |
| Peptide Name | (LLKK)2M |
| Sequence | LLKKLLKKM |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 9 |
| Chirality | L |
| Nature | Cationic |
| Source | Synthetic |
| Origin | NA |
| Species | Mycobacterium tuberculosis |
| Strain | Mycobacterium tuberculosis CSU87 reistant to rifampicin, isoniazid, ethambutol, streptomycin and kanamycin |
| Inhibition Concentartion | MIC = 125 mg/L |
| In vitro/In vivo | In vitro |
| Cell Line | Rat red blood cells (rRBCs) |
| Inhibition Concentartion | NA |
| Cytotoxicity | Very low, i.e. 50% hemolysis concentration (HC50) > 1000 mg/L |
| In vivo Model | None |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | Membrane-lytic mechanism |
| Target | Cell envelope |
| Combination Therapy | None |
| Other Activities | Antibacterial |
| Pubmed ID | 24314557 |
| Year of Publication | 2014 |
| 3-D Structure |  View in Jmol or Download Structure |