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Detailed description page of AntiTbPdb

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antitb_1246 details
Primary information
IDantitb_1246
Peptide Name(LLKK)2M
SequenceLLKKLLKKM
N-terminal ModificationFree
C-terminal ModificationFree
Chemical ModificationNone
Linear/ CyclicLinear
Length9
ChiralityL
NatureCationic
SourceSynthetic
OriginNA
SpeciesMycobacterium tuberculosis
StrainMycobacterium tuberculosis CSU87 reistant to rifampicin, isoniazid, ethambutol, streptomycin and kanamycin
Inhibition ConcentartionMIC = 125 mg/L
In vitro/In vivoIn vitro
Cell LineRat red blood cells (rRBCs)
Inhibition ConcentartionNA
CytotoxicityVery low, i.e. 50% hemolysis concentration (HC50) > 1000 mg/L
In vivo ModelNone
Lethal DoseNA
Immune ResponseNA
Mechanism of ActionMembrane-lytic mechanism
TargetCell envelope
Combination TherapyNone
Other ActivitiesAntibacterial
Pubmed ID24314557
Year of Publication2014
3-D Structure View in Jmol or Download Structure