| Primary information |
|---|
| ID | antitb_1177 |
| Peptide Name | D-LFcin17-30 |
| Sequence | fkcrrwqwrmkklg |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 14 |
| Chirality | D |
| Nature | Cationic |
| Source | Synthetic |
| Origin | NA |
| Species | Mycobacterium avium |
| Strain | Mycobacterium avium strain 2447 smooth transparent variant (SmT) |
| Inhibition Concentartion | IC50 = 10.7 ± 0.9 |
| In vitro/In vivo | In vitro |
| Cell Line | None |
| Inhibition Concentartion | NA |
| Cytotoxicity | NA |
| In vivo Model | None |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | Permeabilization of peptide causes significant changes both in the surface and in the ultrastructural organization of the mycobacterial cells. |
| Target | Cell envelope |
| Combination Therapy | None |
| Other Activities | None |
| Pubmed ID | 24709266 |
| Year of Publication | 2014 |
| 3-D Structure |  View in Jmol or Download Structure |