Primary information |
---|
ID | antitb_1174 |
Peptide Name | LFcin17-30 |
Sequence | FKCRRWQWRMKKLG |
N-terminal Modification | Free |
C-terminal Modification | Free |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Length | 14 |
Chirality | L |
Nature | Cationic |
Source | Protein Derived |
Origin | From bovine lactoferricin |
Species | Mycobacterium avium |
Strain | Mycobacterium avium strain 2-151 smooth transparent variant (SmT) |
Inhibition Concentartion | IC90 = 22.8 ± 9.1 |
In vitro/In vivo | In vitro |
Cell Line | None |
Inhibition Concentartion | NA |
Cytotoxicity | NA |
In vivo Model | None |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | Permeabilization of peptide causes significant changes both in the surface and in the ultrastructural organization of the mycobacterial cells. |
Target | Cell envelope |
Combination Therapy | None |
Other Activities | Antibacterial |
Pubmed ID | 24709266 |
Year of Publication | 2014 |
3-D Structure | View in Jmol or Download Structure |