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Detailed description page of AntiTbPdb

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antitb_1173 details
Primary information
IDantitb_1173
Peptide NameLFcin17-30
SequenceFKCRRWQWRMKKLG
N-terminal ModificationFree
C-terminal ModificationFree
Chemical ModificationNone
Linear/ CyclicLinear
Length14
ChiralityL
NatureCationic
SourceProtein Derived
OriginFrom bovine lactoferricin
SpeciesMycobacterium avium
StrainMycobacterium avium strain 2-151 smooth transparent variant (SmT)
Inhibition ConcentartionIC50 = 8.0 ± 1.5
In vitro/In vivoIn vitro
Cell LineNone
Inhibition ConcentartionNA
CytotoxicityNA
In vivo ModelNone
Lethal DoseNA
Immune ResponseNA
Mechanism of ActionPermeabilization of peptide causes significant changes both in the surface and in the ultrastructural organization of the mycobacterial cells.
TargetCell envelope
Combination TherapyNone
Other ActivitiesAntibacterial
Pubmed ID24709266
Year of Publication2014
3-D Structure View in Jmol or Download Structure