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Detailed description page of AntiTbPdb

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antitb_1156 details
Primary information
IDantitb_1156
Peptide NameNisin S
SequenceI-(Dhb)-AI-(Dha)-LA-(Abu)-PGAK-(Abu)-GALMGANMS-(Abu)-A-(Abu)-ANASIHV-(Dha)-K
N-terminal ModificationFree
C-terminal ModificationFree
Chemical ModificationDha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Linear/ CyclicCyclic (5 hinge region dur to presence of lanthion
Length34
ChiralityL
NatureNA
SourceNatural
OriginProduced by Lactococcus lactis
SpeciesMycobacterium kansasii
StrainMycobacterium kansasii CIT11/06
Inhibition ConcentartionRelative growth was reduced by 29% compared to that which occurred in the presence of nisin A.
In vitro/In vivoIn vitro
Cell LineNone
Inhibition ConcentartionNA
CytotoxicityNA
In vivo ModelNone
Lethal DoseNA
Immune ResponseNA
Mechanism of ActionNA
TargetNA
Combination TherapyNone
Other ActivitiesAntibacterial (Shigella, Pseudomonas and Salmonella, S. aureus, S. agalactiae and L. monocytogenes)
Pubmed ID21468208
Year of Publication2010
3-D StructureNA