Primary information |
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ID | antitb_1095 |
Peptide Name | Seq 36 |
Sequence | RQRRVVIWW |
N-terminal Modification | Free |
C-terminal Modification | Free |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Length | 9 |
Chirality | L |
Nature | Cationic |
Source | Synthetic |
Origin | NA |
Species | Mycobacterium tuberculosis |
Strain | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain |
Inhibition Concentartion | MIC90 = 24.7 μM |
In vitro/In vivo | In vitro |
Cell Line | THP-1 cells |
Inhibition Concentartion | NA |
Cytotoxicity | For THP-1 (infected wth M.tb) IC50 = 197.2 μM |
In vivo Model | None |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | None |
Other Activities | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) |
Pubmed ID | 23478953 |
Year of Publication | 2013 |
3-D Structure | View in Jmol or Download Structure |