Welcome to Entry Card of Peptide


Details of TopicalPdb ID 1657

PRIMARY INFORMATION
ID1657
PMID11062537
Year2000
SequenceAa-MeLeu-MeLeu-MeVal-
3-hydroxy-N,4-dimethyl-L-2-amino-
6-octenoyl-Abu-MeGly-MeLeu-V-MeLeu
NameCyclosporine
Length11
N-Terminal ModificationFree
C-Terminal ModificationFree
Linear/ CyclicCyclic (head to tail)
ChiralityMix
Chemical ModificationAbu= amino butyric acid, MeLeu=N-methyl-Leucine, MeVal=N-methyl-Valine
Origin of PeptideSynthetic
Nature of Peptide/CargoNot mentioned
MechanismNot mentioned
Cargo Sequence/StructureNo cargo
Name of cargo
Not applicable
AssayDual-color fluorescence microscopy.
Enhancer1-mM solution of biotinylated hepta-D-arginine (biotin r7) dissolved in PBS with an equal volume of lotion vehicle.
Properties of enhancerNot mentioned
Concentration1% releasable R7–CsA conjugate
Incubation time1 night
Tissue permeability (value with units)The inflammation was healed in the treated ear.
Tissue Samplemouse and human skin
Ex vivo/In vivo/In vitroin vitro
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN.A.