Welcome to Entry Card of Peptide


Details of TopicalPdb ID 1650

PRIMARY INFORMATION
ID1650
PMID3510926
Year1986
SequenceMALWMRLLPLLALLAL
WGPDPAAAFVNQHLCGSH
LVEALYLVCGERGFFYTPKTR
REAEDLQVGQVELGGGPG
AGSLQPLALEGSLQKRG
IVEQCCTSICSLYQLENYCN
NameInsulin
Length51
N-Terminal ModificationFree
C-Terminal ModificationFree
Linear/ CyclicLinear
ChiralityL
Chemical ModificationNone
Origin of PeptideSynthetic
Nature of Peptide/CargoNot mentioned
MechanismNot mentioned
Cargo Sequence/StructureNo cargo
Name of cargo
Not applicable
AssayRadioimmunoassay
Enhancer0.2-0.8 mA current
Properties of enhancerTo enhance the iontophoretic delivery of insulin in skin.
Concentration10-500 U/ml
Incubation time1 hour
Tissue permeability (value with units)Within one hour of turning the current on, blood glucose levels decreased and serum insulin levels increased.
Tissue Samplemale New Zealand white rabbits.
Ex vivo/In vivo/In vitroin vitro
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)
N1[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
NCC(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@@H]
3C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N4[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N
[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)NCC(=O)NCC(=O)NCC(=O)N5[C@H](C(=O)NCC(=O)N[C@H]
(C(=O)NCC(=O)N[C@H](