ID | 1650 | |
PMID | 3510926 | |
Year | 1986 | |
Sequence | MALWMRLLPLLALLAL WGPDPAAAFVNQHLCGSH LVEALYLVCGERGFFYTPKTR REAEDLQVGQVELGGGPG AGSLQPLALEGSLQKRG IVEQCCTSICSLYQLENYCN | |
Name | Insulin | |
Length | 51 | |
N-Terminal Modification | Free | |
C-Terminal Modification | Free | |
Linear/ Cyclic | Linear | |
Chirality | L | |
Chemical Modification | None | |
Origin of Peptide | Synthetic | |
Nature of Peptide/Cargo | Not mentioned | |
Mechanism | Not mentioned | |
Cargo Sequence/Structure | No cargo | |
Name of cargo | Not applicable | |
Assay | Radioimmunoassay | |
Enhancer | 0.2-0.8 mA current | |
Properties of enhancer | To enhance the iontophoretic delivery of insulin in skin. | |
Concentration | 10-500 U/ml | |
Incubation time | 1 hour | |
Tissue permeability (value with units) | Within one hour of turning the current on, blood glucose levels decreased and serum insulin levels increased. | |
Tissue Sample | male New Zealand white rabbits. | |
Ex vivo/In vivo/In vitro | in vitro | |
STRUCTURE |
| |
SMILES | N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O) N1[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) NCC(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@@H] 3C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N4[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)NCC(=O)NCC(=O)NCC(=O)N5[C@H](C(=O)NCC(=O)N[C@H] (C(=O)NCC(=O)N[C@H]( |