ID | 1648 | |
PMID | 8321834 | |
Year | 1992 | |
Sequence | CYFQNCPRG | |
Name | [Arg 8 ]vasopressin | |
Length | 9 | |
N-Terminal Modification | Free | |
C-Terminal Modification | Free | |
Linear/ Cyclic | Linear | |
Chirality | L | |
Chemical Modification | None | |
Origin of Peptide | Synthetic | |
Nature of Peptide/Cargo | Not mentioned | |
Mechanism | Not mentioned | |
Cargo Sequence/Structure | No cargo | |
Name of cargo | Not applicable | |
Assay | permeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from p-HEMA was measured. | |
Enhancer | PH 3.6 | |
Properties of enhancer | Not mentioned | |
Concentration | 0.65mM | |
Incubation time | 36 hrs | |
Tissue permeability (value with units) | 10.6 (cm/sec) * 10 8 | |
Tissue Sample | skin of hairless rat | |
Ex vivo/In vivo/In vitro | in vitro | |
STRUCTURE |
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SMILES | N[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C (=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H] (CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O) N[C@@H](CS)C(=O)N1CCC[C@H] 1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC=O |