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Details of TopicalPdb ID 1645

PRIMARY INFORMATION
ID1645
PMID8321834
Year1992
SequenceCYFQNCPRG
Name[Arg 8 ]vasopressin
Length9
N-Terminal ModificationFree
C-Terminal ModificationFree
Linear/ CyclicLinear
ChiralityL
Chemical ModificationNone
Origin of PeptideSynthetic
Nature of Peptide/CargoNot mentioned
MechanismNot mentioned
Cargo Sequence/StructureNo cargo
Name of cargo
Not applicable
Assaypermeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from polyacrylamide hydrogels was measured.
EnhancerPH 3.6
Properties of enhancerNot mentioned
Concentration0.65mM
Incubation time36 hrs
Tissue permeability (value with units)61.6(cm/sec) * 10 8
Tissue Sampleskin of hairless rat
Ex vivo/In vivo/In vitroin vitro
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C
(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]
(CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)
N[C@@H](CS)C(=O)N1CCC[C@H]
1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC=O