ID | 1643 | |
PMID | 8321834 | |
Year | 1992 | |
Sequence | MALWMRLLPLLALLAL WGPDPAAAFVNQHLCGSH LVEALYLVCGERGFFYTPKTR REAEDLQVGQVELGGGPG AGSLQPLALEGSLQKRG IVEQCCTSICSLYQLENYCN | |
Name | Insulin(porcine) | |
Length | 51 | |
N-Terminal Modification | Free | |
C-Terminal Modification | Free | |
Linear/ Cyclic | Linear | |
Chirality | L | |
Chemical Modification | None | |
Origin of Peptide | Synthetic | |
Nature of Peptide/Cargo | Not mentioned | |
Mechanism | Not mentioned | |
Cargo Sequence/Structure | No cargo | |
Name of cargo | Not applicable | |
Assay | permeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from Polyacrylamide hydrogels hydrogels was measured | |
Enhancer | PH 3.6 | |
Properties of enhancer | Not mentioned | |
Concentration | 0.65mM | |
Incubation time | 36 hrs | |
Tissue permeability (value with units) | 0.312 (cm/sec) * 10 8 | |
Tissue Sample | skin of hairless rat | |
Ex vivo/In vivo/In vitro | in vitro | |
STRUCTURE |
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SMILES | N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O) N1[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) NCC(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@@H] 3C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N4[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)NCC(=O)NCC(=O)NCC(=O)N5[C@H](C(=O)NCC(=O)N[C@H] (C(=O)NCC(=O)N[C@H]( |