Welcome to Entry Card of Peptide


Details of TopicalPdb ID 1641

PRIMARY INFORMATION
ID1641
PMID3298619
Year1987
SequenceMALWMRLLPLLALLAL
WGPDPAAAFVNQHLCGSH
LVEALYLVCGERGFFYTPKTR
REAEDLQVGQVELGGGPG
AGSLQPLALEGSLQKRG
IVEQCCTSICSLYQLENYCN
NameInsulin
Length51
N-Terminal ModificationFree
C-Terminal ModificationFree
Linear/ CyclicLinear
ChiralityL
Chemical ModificationNone
Origin of Peptidepeptide hormone produced by beta cells of the pancreatic islets
Nature of Peptide/CargoNot mentioned
MechanismNot mentioned
Cargo Sequence/StructureNo cargo
Name of cargo
Not applicable
AssayDirect radioactive counting or the radio immunoassay of plasma
EnhancerSolution pH 3.68
Properties of enhancerNot mentioned
ConcentrationReservoir electrode was filled with 3ml of aqueous insulin solution.
Incubation time60 minutes
Tissue permeability (value with units)Glucose level decreased from 280 mg/dL to 220 mg/dL
Tissue SampleSkin of 50 hairless rats and 12 regular rats.
Ex vivo/In vivo/In vitroin vitro
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)
N1[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
NCC(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@@H]
3C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N4[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N
[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)NCC(=O)NCC(=O)NCC(=O)N5[C@H](C(=O)NCC(=O)N[C@H]
(C(=O)NCC(=O)N[C@H](