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Details of TopicalPdb ID 1637

PRIMARY INFORMATION
ID1637
PMID2664126
Year1989
SequenceCYFQNCPRG
NameArginine-Vasopressin
Length9
N-Terminal ModificationFree
C-Terminal ModificationFree
Linear/ CyclicLinear
ChiralityL
Chemical ModificationNone
Origin of PeptideSynthetic
Nature of Peptide/Cargononapeptide hormone
MechanismNot mentioned
Cargo Sequence/StructureNo cargo
Name of cargo
Not applicable
AssayIontophoresis permetaion studies
Enhancercitrate phosphate buffer, at pH 5 or pH 7. (~0.06 M ionic strength)
Properties of enhancerNot mentioned
Concentration0.08 mM
Incubation timeThe amount of AVP permeating through the skin was monitored during the current application and then for another 5 hrs after the termination of
Tissue permeability (value with units)2.71(+- 0.25)nmol/cm2h+-S.D
Tissue Sampleabdominal region of hairless mouse
Ex vivo/In vivo/In vitroin vitro
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C
(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]
(CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)
N[C@@H](CS)C(=O)N1CCC[C@H]
1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC=O