| PRIMARY INFORMATION |
|---|
| ID | 1626 |
| PMID | 2203894 |
| Year | 1989 |
| Sequence | HIITDPNMAEYL 4.18 |
| Name | GnRH analogue 1 |
| Length | 10 |
| N-Terminal Modification | [Ac-D2Nal,r D4CIPhe,* D3Pal,3 NicLys,s DNicLys,G |
| C-Terminal Modification | Free |
| Linear/ Cyclic | Linear |
| Chirality | L |
| Chemical Modification | [Ac-D2Nal,r D4CIPhe,* D3Pal,3 NicLys,s DNicLys,G Ilys,S DAlalO] |
| Origin of Peptide | Analog of growth hormone |
| Nature of Peptide/Cargo | Gonadotropin releasing hormone |
| Mechanism | Not mentioned |
| Cargo Sequence/Structure | No cargo |
Name of cargo
| Not applicable |
| Assay | HPLC |
| Enhancer | Sorensen's phosphate buffer |
| Properties of enhancer | Curents employed ranged from 0.1 to 0.5 mA cm -2 |
| Concentration | 400 ul |
| Incubation time | 1-5 hrs |
| Tissue permeability (value with units) | Iontophoresis of aqueous solutions of 1 was not very successful. It was only marginally soluble and as iontophoresis proceeded, the donor solution became inhomogeneous. Flux rates were negligible. |
| Tissue Sample | hairless mouse Skin |
| Ex vivo/In vivo/In vitro | in vitro |
| SECONDARY INFORMATION |
|---|
| STRUCTURE | |
| SMILES | N.A. |
