ID | 1615 | |
PMID | 25041740 | |
Year | 2014 | |
Sequence | LLGDFFRKSKEKIGK EFKRIVQRIKDFLRN LVPRTES | |
Name | LL-37 | |
Length | 37 | |
N-Terminal Modification | Free | |
C-Terminal Modification | Free | |
Linear/ Cyclic | Linear | |
Chirality | L | |
Chemical Modification | None | |
Origin of Peptide | Synthetic | |
Nature of Peptide/Cargo | Not mentioned | |
Mechanism | Not well understood | |
Cargo Sequence/Structure | None | |
Name of cargo | Not applicable | |
Assay | Statistical analysis was done in order to measure the efficacy of LL-37 as a drug. | |
Enhancer | None | |
Properties of enhancer | Not applicable | |
Concentration | 1.6mg/ml | |
Incubation time | 4 weeks | |
Tissue permeability (value with units) | The ulcers decreased to 50% | |
Tissue Sample | Human skin | |
Ex vivo/In vivo/In vitro | in vitro | |
STRUCTURE |
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SMILES | N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C=O)CO)CCC(=O)O) [C@H](O)C)CCCNC(=N)N)CCC)C(C)C)CC (C)C)CC(=O)N)CCCNC(=N)N)CC(C)C)Cc1 ccccc1)CC(=O)O)CCCCN)[C@H](CC)C)CCCNC(=N)N) CCC(=O)N)C(C)C)[C@H](CC)C)CCCNC(=N)N)CCCCN) Cc1ccccc1)CCC(=O)O)CCCCN)[C@H](CC)C)CCCCN) CCC(=O)O)CCCCN)CO)CCCCN)CCCNC(=N)N)Cc1ccccc1) Cc1ccccc1)CC(=O)O)CC(C)C)CC(C)C |