| PRIMARY INFORMATION |
|---|
| ID | 1608 |
| PMID | 17307377 |
| Year | 2007 |
| Sequence | T |
| Name | Capsaicin |
| Length | 1 |
| N-Terminal Modification | Free |
| C-Terminal Modification | 7-methyl octa-5-ene |
| Linear/ Cyclic | Linear |
| Chirality | L |
| Chemical Modification | OH on benzene ring of tyrosine |
| Origin of Peptide | Component of chili peppers |
| Nature of Peptide/Cargo | Capsaicin increases calcitonin gene-related peptide (CGRP) release from sensory neurons by stimulating vanilloid receptor-1 |
| Mechanism | Not mentioned |
| Cargo Sequence/Structure | None |
Name of cargo
| Not applicable |
| Assay | Immunoassay. |
| Enhancer | Not mentioned |
| Properties of enhancer | Not mentioned |
| Concentration | 0.01% |
| Incubation time | 30 minutes |
| Tissue permeability (value with units) | Dermal IGF level increased to approximately 2000 ng/g tissue |
| Tissue Sample | Mice skin |
| Ex vivo/In vivo/In vitro | in vitro |
| SECONDARY INFORMATION |
|---|
| STRUCTURE | |
| SMILES | N.A. |