PRIMARY INFORMATION |
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ID | 1590 |
PMID | 25786877 |
Year | 2013 |
Sequence | AW |
Name | Alanine-tryptophan |
Length | 2 |
N-Terminal Modification | Free |
C-Terminal Modification | Free |
Linear/ Cyclic | Linear |
Chirality | L |
Chemical Modification | None |
Origin of Peptide | Synthetic |
Nature of Peptide/Cargo | Not mentioned |
Mechanism | Not mentioned |
Cargo Sequence/Structure | None |
Name of cargo
| Not applicable |
Assay | electroosmotic volume flux was observed to study peptide penetration |
Enhancer | The donor solution pH was maintained at physiological pH 7.4 or at pH levels 6.0, 5.5, 5.0 and 3 using 0.1 or 0.01 M sodium hydroxide (NaOH) and/or 0.1 or 0.01 M hydrochloric acid (HCl) solutions. |
Properties of enhancer | Not mentioned |
Concentration | 1-10 mg/ml |
Incubation time | Not mentioned |
Tissue permeability (value with units) | Skin permeability of peptide increased 30 times more than passive permeation. |
Tissue Sample | Human epidermal membrane |
Ex vivo/In vivo/In vitro | in vitro |
SECONDARY INFORMATION |
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STRUCTURE | |
SMILES | N[C@@H](C)C(=O)N[C@@H](Cc1c [nH]c2ccccc12)C=O |