| PRIMARY INFORMATION |
|---|
| ID | 1400 |
| PMID | 2480171 |
| Year | 1989 |
| Sequence | T |
| Name | Capsaicin |
| Length | 1 |
| N-Terminal Modification | Free |
| C-Terminal Modification | 7-methyl octa-5-ene |
| Linear/ Cyclic | Linear |
| Chirality | L |
| Chemical Modification | OH on benzene ring of tyrosine |
| Origin of Peptide | Component of chili peppers |
| Nature of Peptide/Cargo | Capsaicin activates sensory nerve endings in the nose and the paranasal sinuses, thereby stimulating protective reflexes involved in sneezing and in increased vasopermeability and stimulate mucociliary activity |
| Mechanism | Not mentioned |
| Cargo Sequence/Structure | None |
Name of cargo
| Not applicable |
| Assay | The amount of nasal mucosa secreted in response to capsaicin was weighed. |
| Enhancer | None |
| Properties of enhancer | Not applicable |
| Concentration | 1630nmol |
| Incubation time | 6 days |
| Tissue permeability (value with units) | Capsaicin stimulated the secretion of nasal fluid in a dose-dependent manner when administered as a single dose. |
| Tissue Sample | Nasal mucosa of rats |
| Ex vivo/In vivo/In vitro | in vivo |
| SECONDARY INFORMATION |
|---|
| STRUCTURE | |
| SMILES | N.A. |
