| PRIMARY INFORMATION |
|---|
| ID | 1398 |
| PMID | 7680838 |
| Year | 1993 |
| Sequence | T |
| Name | Capsaicin |
| Length | 1 |
| N-Terminal Modification | Free |
| C-Terminal Modification | 7-methyl octa-5-ene |
| Linear/ Cyclic | Linear |
| Chirality | L |
| Chemical Modification | OH on benzene ring of tyrosine |
| Origin of Peptide | Component of chili peppers |
| Nature of Peptide/Cargo | Affects not only sensory nerves but impacts on THI sympathetic nerves in the nasal mucosa |
| Mechanism | Not mentioned |
| Cargo Sequence/Structure | None |
Name of cargo
| Not applicable |
| Assay | Immunocytochemistry |
| Enhancer | None |
| Properties of enhancer | Not applicable |
| Concentration | 10-2 Capsaicin soln. |
| Incubation time | 3 days |
| Tissue permeability (value with units) | In the nasal mucosa of toluene diisocyanate sensitized guinea pigs, substance P (SP)- and tyrosine hydroxylase (TH)-like immunoreactive (SPI and THI) fibers seemed to decrease after capsaicin application |
| Tissue Sample | Nasal mucosa of guinea pigs |
| Ex vivo/In vivo/In vitro | in vivo |
| SECONDARY INFORMATION |
|---|
| STRUCTURE | |
| SMILES | N.A. |
