Welcome to Entry Card of Peptide

Details of TopicalPdb ID 1380

PRIMARY INFORMATION
ID	1380
PMID	20089796
Year	2010
Sequence	SKYALVDASLKMSDP NRFRGKDLPVLDQL
Name	HSV-1 gD 1-29 (group1)
Length	29
N-Terminal Modification	Free
C-Terminal Modification	Free
Linear/ Cyclic	Linear
Chirality	L
Chemical Modification	None
Origin of Peptide	T-cell epitope peptide identified from HSV1-gD
Nature of Peptide/Cargo	Intranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses
Mechanism	Not mentioned
Cargo Sequence/Structure	None
Name of cargo	Not applicable
Assay	FACS
Enhancer	CpG adjuvant
Properties of enhancer	Not mentioned
Concentration	12.5µl 50 µl per nasal cavity
Incubation time	Immunized on 0,14 and 21 days. Euthanized after 10 days.
Tissue permeability (value with units)	Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels.
Tissue Sample	Nasal cavity of New Zealand White rabbits
Ex vivo/In vivo/In vitro	in vivo
SECONDARY INFORMATION
STRUCTURE	Predicted Structure
SMILES	N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N1[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C(=O)N[C@H](C=O)CC(C)C)CCC(=O)N)CC(=O) O)CC(C)C)C(C)C)CCC1)CC(C)C)CC(=O)O) CCCCN)CCCNC(=N)N)Cc1ccccc1)CCCNC(=N) N)CC(=O)N)CCC)CC(=O)O)CO)CCSC)CCCCN)CC(C) C)CO)C)CC(=O)O)C(C)C)CC(C)C)C)Cc1ccc(cc1)O) CCCCN)CO