| ID | 1368 | |
| PMID | 20891012 | |
| Year | 2010 | |
| Sequence | GRKKRRQRRRPPQRKC MSKGEELFTGVVPILV ELDGDVNGHKFSVSGE GEGDATYGKLTLKFIC TTGKLPVPWPTLVTTF SYGVQCFSRYPDHMKQ HDFFKSAMPEGYVQE RTIFFKDDGNYKTRAE VKFEGDTLVNRIELKG IDFKEDGNILGHKLEY NYNSHNVYIMADKQKN GIKVNFKIRHNIEDGS VQLADHYQQNTPIGDG PVLLPDNHYLSTQSAL SKDPNEKRDHMVLLEF | |
| Name | N-terminal Tat fusion green fluorescent protein (GFP) (TG) | |
| Length | 254 | |
| N-Terminal Modification | Free | |
| C-Terminal Modification | Free | |
| Linear/ Cyclic | Linear | |
| Chirality | L | |
| Chemical Modification | None | |
| Origin of Peptide | Synthetic fusion protein of TAT and GFP | |
| Nature of Peptide/Cargo | Fluorescent CPP | |
| Mechanism | Not mentioned | |
| Cargo Sequence/Structure | None | |
| Name of cargo | Not applicable | |
| Assay | Vertical Franz diffusion cell | |
| Enhancer | TG loaded in non-elastic anionic niosomes (Tween 61/CHL/DP at 1:1:0.05 molar ratio) | |
| Properties of enhancer | Not mentioned | |
| Concentration | 10µM | |
| Incubation time | 6 hours | |
| Tissue permeability (value with units) | Cumulative amounts 22.03 ± 4.01 µg/cm2 and fluxes 3.67 ± 2.33 µg/cm2·h for stratum corneum. The receiver compartment of Franz Diffusion Cells had cumulative amount=30.24 ± 4.81 µg/cm2 and fluxes= 5.04 ± 0.80 µg/cm2·h | |
| Tissue Sample | Stratum corneum of the abdominal skin of Sparague-Dawley rats after shaving off hair | |
| Ex vivo/In vivo/In vitro | ex vivo | |
| STRUCTURE |
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| SMILES | N.A. | |