Welcome to Entry Card of Peptide


Details of TopicalPdb ID 1365

PRIMARY INFORMATION
ID1365
PMID20891012
Year2010
SequenceMSKGEELFTGVVPILV
ELDGDVNGHKFSVSGE
GEGDATYGKLTLKFIC
TTGKLPVPWPTLVTTF
SYGVQCFSRYPDHMKQ
HDFFKSAMPEGYVQER
TIFFKDDGNYKTRAEV
KFEGDTLVNRIELKGI
DFKEDGNILGHKLEYN
YNSHNVYIMADKQKNG
IKVNFKIRHNIEDGSV
QLADHYQQNTPIGDGP
VLLPDNHYLSTQSALS
KDPNEKRDHMVLLEFV
TAAGITHGMDELYK
NameGFP
Length238
N-Terminal ModificationFree
C-Terminal ModificationFree
Linear/ CyclicLinear
ChiralityL
Chemical ModificationNone
Origin of PeptideAequorea victoria (Jellyfish)
Nature of Peptide/CargoFluorescent protein
MechanismNot mentioned
Cargo Sequence/StructureNone
Name of cargo
Not applicable
AssayVertical Franz diffusion cell
EnhancerGFP solution in 100 mM phosphate buffer (pH 7.0)
Properties of enhancerNot mentioned
Concentration10µM
Incubation time6 hours
Tissue permeability (value with units)Cumulative amounts 24.15 ± 7.28 µg/cm2 and fluxes 4.02 ± 1.21 µg/cm2·h for stratum corneum. The receiver compartment of Franz Diffusion Cells had cumulative amount=22.61 ± 2.87 µg/cm2 and fluxes= 3.77 ± 0.48 µg/cm2·h
Tissue SampleStratum corneum of the abdominal skin of Sparague-Dawley rats after shaving off hair
Ex vivo/In vivo/In vitroex vivo
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN.A.