| ID | 1364 | |
| PMID | 20891012 | |
| Year | 2010 | |
| Sequence | GRKKRRQRRRPPQRKC MSKGEELFTGVVPILV ELDGDVNGHKFSVSGE GEGDATYGKLTLKFIC TTGKLPVPWPTLVTTF SYGVQCFSRYPDHMKQ HDFFKSAMPEGYVQE RTIFFKDDGNYKTRAE VKFEGDTLVNRIELKG IDFKEDGNILGHKLEY NYNSHNVYIMADKQKN GIKVNFKIRHNIEDGS VQLADHYQQNTPIGDG PVLLPDNHYLSTQSAL SKDPNEKRDHMVLLEF | |
| Name | N-terminal Tat fusion green fluorescent protein (GFP) (TG) | |
| Length | 254 | |
| N-Terminal Modification | Free | |
| C-Terminal Modification | Free | |
| Linear/ Cyclic | Linear | |
| Chirality | L | |
| Chemical Modification | None | |
| Origin of Peptide | Synthetic fusion protein of TAT and GFP | |
| Nature of Peptide/Cargo | Fluorescent CPP | |
| Mechanism | Not mentioned | |
| Cargo Sequence/Structure | None | |
| Name of cargo | Not applicable | |
| Assay | Vertical Franz diffusion cell | |
| Enhancer | GFP solution in 100 mM phosphate buffer (pH 7.0) | |
| Properties of enhancer | Not mentioned | |
| Concentration | 10µM | |
| Incubation time | 6 hours | |
| Tissue permeability (value with units) | Cumulative amounts 4.86 ± 0.55 µg/cm2 and fluxes 0.81 ± 0.09 µg/cm2·h for stratum corneum. The receiver compartment of Franz Diffusion Cells had cumulative amount=28.50 ± 12.07 µg/cm2 and fluxes= 4.75 ± 1.47 µg/cm2·h | |
| Tissue Sample | Stratum corneum of the abdominal skin of Sparague-Dawley rats after shaving off hair | |
| Ex vivo/In vivo/In vitro | ex vivo | |
| STRUCTURE |
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| SMILES | N.A. | |