| ID | 1140 | |
| PMID | 17493711 | |
| Year | 2009 | |
| Sequence | TRWYSMKKTTMKIIP FNRL | |
| Name | Haptide | |
| Length | 19 | |
| N-Terminal Modification | Free | |
| C-Terminal Modification | Free | |
| Linear/ Cyclic | Linear | |
| Chirality | L | |
| Chemical Modification | None | |
| Origin of Peptide | Cell binding and penetrating 20-mer fibrinopeptides derivative | |
| Nature of Peptide/Cargo | Improve the cell penetration and subsequent presentation of the antigen. | |
| Mechanism | Not mentioned | |
| Cargo Sequence/Structure | Not mentioned | |
| Name of cargo | Heat labile enterotoxin (nLT) | |
| Assay | Anti-LT antibodies determination by ELISA | |
| Enhancer | None | |
| Properties of enhancer | Not applicable | |
| Concentration | 100 µg/mouse | |
| Incubation time | 3 times at two-week interval | |
| Tissue permeability (value with units) | Significant increase in antibody titer (anti-LT) in the serum of mice on topical application with HR-gp100H | |
| Tissue Sample | Ears of BALB/c mice | |
| Ex vivo/In vivo/In vitro | in vitro | |
| STRUCTURE |
| |
| SMILES | N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N [C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C (=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3]) C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O) N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C (=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N) C(=O)N[C@@H](CC(C)C)C=O | |