ID | 1091 | |
PMID | 22189681 | |
Year | 2011 | |
Sequence | RKKRRQRRR | |
Name | Tat | |
Length | 9 | |
N-Terminal Modification | Free | |
C-Terminal Modification | Free | |
Linear/ Cyclic | Linear | |
Chirality | L | |
Chemical Modification | None | |
Origin of Peptide | HIV-1 | |
Nature of Peptide/Cargo | Tat-SOD is anti-inflammatory | |
Mechanism | Tat-SOD slightly suppressed COX-2, IL-6 and IL-1β expression | |
Cargo Sequence/Structure | Not available | |
Name of cargo | SOD | |
Assay | Histochemical analysis | |
Enhancer | None | |
Properties of enhancer | Not applicable | |
Concentration | 2µg/ear of mice | |
Incubation time | 4 days | |
Tissue permeability (value with units) | Significant permeability of the Tat-SOD peptide can be seen in histochemical images | |
Tissue Sample | Ear of mice | |
Ex vivo/In vivo/In vitro | in vivo | |
STRUCTURE |
| |
SMILES | N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H] (CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N [C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N) C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC (=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2]) N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O |