Welcome to Entry Card of Peptide


Details of TopicalPdb ID 1054

PRIMARY INFORMATION
ID1054
PMID22890441
Year2012
Sequenceβ-Ala-H
NameN-acetyl- L -carnosine
Length2
N-Terminal ModificationAcetylation
C-Terminal ModificationFree
Linear/ CyclicLinear
ChiralityL
Chemical Modificationβ-Alanine
Origin of PeptideSynthetic
Nature of Peptide/CargoAntioxidant
MechanismIt acts as antioxidant with its hydroxyl-radical-, singlet oxygen-scavenging and lipid peroxidase activities.
Cargo Sequence/StructureNone
Name of cargo
Not applicable
AssayFranz diffusion cell, HPLC
EnhancerMicroemulsion (ME-PG)
Properties of enhancerME is a colloidal carrier system which high solubilization capacity, noninvasive administration or easy preparation and application
Concentration20mg of formulation
Incubation time30 minutes
Tissue permeability (value with units)~3% of applied dose
Tissue SampleEpidermis of human breast skin
Ex vivo/In vivo/In vitroex vivo
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESCC(=O)NC[C@@H](C)C(=O)N[C@@H](Cc1nc[nH]c1)C=O