Browse result page of TopicalPdb


Please click on the ID to see detailed information about each entry.

The total number entries retrieved from this search are
ID1345SequencepGlu-EDSGNameEpidermal pentapeptideNature of peptide or cargoIt induces a moderate but long-lasting inhibition of epidermal cell proliferation when given at low (picomol) doses but stimulates epidermal cell proliferation at higher dosesAssayColcemid-arrested mitoses and labelled cells were counted per 12 mm of interfollicular epidermis in 5 pm paraffin sections stationed with haematoxylin in the former and dipcoated with NTB 2 emulsion and incubated for 3 weeks at 0-4 ͦC for later. The statistical evaluations were made according to the Wilcoxon's rank sum test.Tissue permeabilitySignificant mitotic rate inhibition initially and on day 7 after an overshoot on day 6Tissue SampleBack skin of female hairless mice (hr/hr)PUBMED ID1977237
ID1346SequencepGlu-EDSGNameEpidermal pentapeptideNature of peptide or cargoIt induces a moderate but long-lasting inhibition of epidermal cell proliferation when given at low (picomol) doses but stimulates epidermal cell proliferation at higher dosesAssayColcemid-arrested mitoses and labelled cells were counted per 12 mm of interfollicular epidermis in 5 pm paraffin sections stationed with haematoxylin in the former and dipcoated with NTB 2 emulsion and incubated for 3 weeks at 0-4 ͦC for later. The statistical evaluations were made according to the Wilcoxon's rank sum test.Tissue permeabilityInitial increase in mitotic rate, peaking on day 2, from day 2 to day 10, mitotic rate was lower than normal.Tissue SampleBack skin of female hairless mice (hr/hr)PUBMED ID1977237
ID1347SequencepGlu-EDSGNameEpidermal pentapeptideNature of peptide or cargoIt induces a moderate but long-lasting inhibition of epidermal cell proliferation when given at low (picomol) doses but stimulates epidermal cell proliferation at higher dosesAssayColcemid-arrested mitoses and labelled cells were counted per 12 mm of interfollicular epidermis in 5 pm paraffin sections stationed with haematoxylin in the former and dipcoated with NTB 2 emulsion and incubated for 3 weeks at 0-4 ͦC for later. The statistical evaluations were made according to the Wilcoxon's rank sum test.Tissue permeabilityThe mitotic rate was strongly increased with peaks at days 1, 3 and 6 (twice the control value).Tissue SampleBack skin of female hairless mice (hr/hr)PUBMED ID1977237