A database of FDA approved therapeutic peptides and proteins
| ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1425 | Th1071 | Pancrelipase | Pancreatic alpha amy Full view | 1206 | Ia | Metabolic/genetic/ | PERTZYE | Digestive care US, Inc. | Beige-white amorphous powder, miscible in water and practically insoluble or insoluble in alcohol and ether PERTZYE delayed-release capsule | Oral route | Gastrointestinal Agents and Enzyme Replacement Agents | Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch |
| 1428 | Th1072 | Streptokinase | MKNYLSFGMFALLFALTFGT Full view | 440 | Ic | Metabolic/Haemetological | Streptase | CSL Behring | Sterile, purified preparation formulated as lypholized powder | Intravenous and intracoronary administration. | Fibrinolytic Agents and Thrombolytic Agents | N.A. |
| 1439 | Th1077 | Urofollitropin | Alpha chain:APDVQDCP Full view | 203 | Ib | Hormonal | BRAVELLE | Ferring Pharmaceuticals Inc. | Sterile, lyophilized powder used after reconstitution with sterile 0.9% Sodium Chloride Injection | Intramuscular and Subcutaneous administration | Fertility Agents | Glutamate carboxypeptidase 2 |
| 1442 | Th1078 | Efalizumab | Light Chain:DIQMTQSP Full view | 229 | IIa | Immunological | RAPTIVA | Genentech, Inc. | Sterile, white to off-white, lyophilized powder in single-use glass vials | Subcutaneous injection. | Immunosuppressive Agents | Iduronic acid |
| 1453 | Th1083 | Coagulation Factor Ix | YNSGKLEEFVQGNLERECME Full view | 415 | Ia | Hematological/Metabolic/genetic | Alprolix | Biogen Idec Inc., and Genentech USA, Inc | Sterile, non-pyrogenic, preservative-free, white to off-white, lyophilized powder to cake for reconstitution with the provided diluent | Intravenous infusion | Coagulants and Thrombotic Agents | N.A. |
| 1455 | Th1085 | Agalsidase Beta | LDNGLARTPTMGWLHWERFM Full view | 398 | Ia | Metabolic | Fabrazyme | Genzyme Corp | Sterile, nonpyrogenic, white to off-white, lyophilized cake or powder for reconstitution with Sterile Water for Injection | N.A. | Enzyme Replacement Agents | N.A. |
| 1456 | Th1086 | Interferon Alfa-2B, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | INTRON® A | Merck | Powder or solution | Intramuscular, Subcutaneous, Intralesional, or Intravenous injection | Immunosuppressive Agents | Granulocyte colony-stimulating factor receptor,Neutrophil elastase, Coagulation factor X,Coagulation factor XI,Coagulation factor VII,Coagulation factor VIII,Prothrombin,Prolow-density lipoprotein receptor-related protein 1,Vitamin K-dependent gamma-carboxylase, Platelet-derived growth factor receptor beta,Platelet-derived growth factor receptor alpha,Alpha-2-macroglobulin |
| 1462 | Th1088 | Enfuvirtide | YTSLIHSLIEESQNQQEKNE Full view | 36 | IIa | Infectious | `FUZEON | Trimeris, Roche | White to off-white, sterile, lyophilized powder. | Subcutaneous injection | HIV Fusion Inhibitors | Oxytocin receptor,Oxytocin-neurophysin 1, Envelope glycoprotein |
| 1477 | Th1097 | Alglucosidase Alfa | AHPGRPRAVPTQCDVPPNSR Full view | 882 | Ic | Metabolic | LUMIZYME | Genzyme | Sterile, nonpyrogenic, white to off-white, lyophilized cake or powder for reconstitution with 10.3 Ml Sterile Water for Injection, USP | Intravenous infusion | Enzyme Replacement Agents | Cation-dependent mannose-6-phosphate receptor,Glycogen |
| 1479 | Th1098 | Exenatide | HGEGTFTSDLSKQMEEEAVR Full view | 39 | Ib | Hormonal/Metabolic | BYDUREON | Amylin Pharmaceuticals | White to off-white powder that is available in a dosage strength of 2 mg exenatide per vial or per pen | N.A. | Hypoglycemic Agents | Glucagon-like peptide 1 receptor |
| 1495 | Th1102 | Abatacept | MHVAQPAVVLASSRGIASFV Full view | 357 | IIa | Immunological | ORENCIA | Bristol-Myers Squibb | Lyophilized powder, supplied as a sterile, white, preservative-free, lyophilized powder for intravenous administration | Intravenous infusion and Subcutaneous injection | Antirheumatic Agents and Immunosuppressive Agents | T-lymphocyte activation antigen CD80,T-lymphocyte activation antigen CD86 |
| 1530 | Th1109 | Nesiritide | SPKMVQGSGCFGRKMDRISS Full view | 32 | Ib | Cardiac | NATRECOR | Scios unit of Johnson & Johnson, | White- to off-white lyophilized powder | Intravenous injection | N.A. | N.A. |
| 1537 | Th1116 | Canakinumab | H-GAMMA-1 (VH(1-118) Full view | 842 | IIIb | Immunological | ILARIS | Novartis Pharmaceuticals | White, preservative-free, lyophilized powder | Subcutaneous injection | Anti-Inflammatory Agents and Monoclonal antibodies | Interleukin-1 beta |
| 1562 | Th1122 | Rilonacept | rilonacept|Homo sapi Full view | 880 | IIa | Immunological | Arcalyst | Regeneron Pharmaceuticals | Sterile, white to off-white, lyophilized powder | Subcutaneous injection | Immunosuppressive Agents | Interleukin-1 beta,Interleukin-1 alpha,Interleukin-1 receptor antagonist protein |
| 1596 | Th1126 | Belatacept | MHVAQPAVVLASSRGIASFV Full view | 357 | IIa | Immunological | Nulojix | Bristol-Myers Squibb | Sterile, white or off-white lyophilized powder | Intravenous injection | Antirheumatic Agents and Immunosuppressive Agents | T-lymphocyte activation antigen CD86,T-lymphocyte activation antigen CD80 |
| 1602 | Th1128 | Velaglucerase Alfa | ARPCIPKSFGYSSVVCVCNA Full view | 497 | Ia | Hormonal | VPRIV | Shire | Sterile, preservative free, lyophilized powder | Intravenous infusion | Enzymes | Glucosylceramidase |
| 1603 | Th1129 | Tesamorelin | YADAIFTNSYRKVLGQLSAR Full view | 44 | Ib | Hormonal | Egrifta | Theratechnologies | Sterile, white to off-white, preservative-free lyophilized powder | Subcutaneous injection | N.A. | Growth hormone-releasing hormone receptor |
| 1604 | Th1130 | Brentuximab Vedotin | Heavy chain:QIQLQQSG Full view | 664 | IIb | Cancer | Adcetris | Seattle Genetics | Sterile, white to off-white, preservative-free lyophilized cake or powder in single-use vials. | Intravenous infusion | N.A. | Tumor necrosis factor receptor superfamily member 8 |
| 1609 | Th1132 | Belimumab | N.A. Full view | 0 | IIa | Immunological | Benlysta | GlaxoSmithKline | Sterile, white to off-white, preservative-free, lyophilized powder | Intravenous infusion | Monoclonal antibodies | Tumor necrosis factor ligand superfamily member 13B |
| 1621 | Th1134 | Asparaginase Erwinia Chrysanthemi | ADKLPNIVILATGGTIAGSA Full view | 327 | Ic | Hormonal | Erwinaze | EUSA Pharma | Sterile, lyophilized, white powder in vials. | Intramuscular injection | Enzymes | N.A. |
| 1623 | Th1136 | Glucarpidase | ALAQKRDNVLFQAATDEQPA Full view | 393 | Ic | Hormonal | Voraxaze | BTG International | Sterile, preservative-free, white lyophilized powder in single-use vials | Intravenous injection | Enzymes | Methotrexate |
| 1628 | Th1139 | Certolizumab Pegol | Light chain: DIQMTQS Full view | 443 | IIb | Immunologcal | Cimzia | UCB | Sterile, white, lyophilized powder for solution or as a sterile, solution in a single-use prefilled 1 mL glass syringe | Subcutaneous injection | TNF inhibitor | Tumor necrosis factor |
| 1638 | Th1144 | Follitropin Alpha | N.A. Full view | 0 | Ib | Adjunct therapy/ Hormonal | Gonal-F | Serono Laboratories | Sterile, lyophilized powder. | Subcutaneous injection | N.A. | N.A. |
| 1640 | Th1145 | Romiplostim | Thrombopoietin recep Full view | 269 | Ib | Immunologcal | Nplate | Amgen | Sterile, preservative-free, lyophilized, solid white powder | Subcutaneous injection | Colony-Stimulating Factors and Thrombopoietic Agents | N.A. |
| 1655 | Th1151 | Somatotropin Recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 192 | Ib | Hormonal/Metabolic | NutropinAQ | Genentech Inc. | Sterile, white lyophilized powder intended for subcutaneous administration after reconstitution with Bacteriostatic Water | Subcutaneous administration | Hormone Replacement Agents | Growth hormone receptor, Prolactin receptor |
| 1656 | Th1151 | Somatotropin Recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 192 | Ib | Hormonal/Metabolic | BioTropin | Bio-Technology General (Israel) Ltd. | Sterile, white, lyophilized powder | Subcutaneous administration | Hormone Replacement Agents | Growth hormone receptor, Prolactin receptor |
| 1657 | Th1151 | Somatotropin Recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 192 | Ib | Hormonal/Metabolic | Protropin | Genentech Inc. | Sterile, white, lyophilized powder | Intramuscular or subcutaneous administration | Hormone Replacement Agents | Growth hormone receptor, Prolactin receptor |
| 1659 | Th1152 | Drotrecogin alfa | Heavy Chain: LIDGKMT Full view | 402 | Ib | Infectious | Xigris | Eli Lilly and Company | Sterile, lyophilized, white to off-white powder | Intravenous Infusion | Antisepsis | Coagulation factor VIII, V, Plasminogen activator inhibitor 1, Thrombomodulin, Vitamin K-dependent protein S, Ceruloplasmin, Prothrombin, Platelet factor 4, Plasma serine protease inhibitor, Serpin B6, Vitamin K-dependent gamma-carboxylase, Endothelial protein C receptor |
| 1661 | Th1153 | Alefacept | Heavy Chain: CFSQQIY Full view | 705 | IIa | Immunological | Amevive | Astellas Pharma Inc. | Sterile, white-to-off-white, preservative-free, lyophilized powder | Intramuscular Injection | Dermatologic and Immunosupressive agents | T-cell surface antigen CD2, Complement C1r subcomponent, Complement C1q subcomponent subunit A, B, C, Low affinity immunoglobulin gamma Fc region receptor III-A,III-B, II-a, II-b, II-c |
| 1663 | Th1155 | Urokinase | KPSSPPEELKFQCGQKTLRP Full view | 276 | Ib | Haemetological | Kinlytic | N.A. | Sterile lyophilized white powder | Intravenous infusion | N.A. | Plasminogen,Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, Tissue-type plasminogen activator, Plasminogen activator inhibitor 1, 2, Plasma serine protease inhibitor, Low-density lipoprotein receptor-related protein 2, Suppressor of tumorigenicity 14 protein, Nidogen-1 |
| 1664 | Th1156 | Abarelix | N.A. Full view | 0 | IIIc | Hormonal | Plenaxis | Speciality european pharma | White to off-white sterile dry powder | Intramuscular Injection | Anti-Testosterone Agents | Gonadotropin-releasing hormone receptor |
| 1666 | Th1157 | Sermorelin | YADAIFTNSYRKVLGQLSAR Full view | 30 | Ia | Hormonal | Sermorelin acetate | Emd serono inc | Sterile, non-pyrogenic, lyophilized powder | Subcutaneous Injection | Hormone Replacement Agents | Growth hormone-releasing hormone receptor |
| 1671 | Th1159 | Gemtuzumab ozogamicin | Light Chain 1: QIVLT Full view | 459 | IIb | Cancer | Mylotarg | Wyeth pharmaceuticals inc | Sterile, white, preservative-free lyophilized powder | Intravenous infusion | Antineoplastic agents and Immunotoxins | Myeloid cell surface antigen CD33, Low affinity immunoglobulin gamma Fc region receptor III-B, Complement C1r subcomponent, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, Low affinity immunoglobulin gamma Fc region receptor III-A, Complement C1s subcomponent, High affinity immunoglobulin gamma Fc receptor I, Low affinity immunoglobulin gamma Fc region receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c |
| 1674 | Th1161 | Albiglutide | HGEGTFTSDVSSYLEGQAAK Full view | 645 | Ib | Hormonal disorders | Eperzan | Glaxosmithkline Inc | Powder for Solution | Subcutaneous | Drugs used in diabetes; alimentary tract and metabolism; blood glucose lowering drugs, excl. insulins. | Glucagon-like peptide 1 receptor |
| 1676 | Th1161 | Albiglutide | HGEGTFTSDVSSYLEGQAAK Full view | 645 | Ib | Hormonal disorders | Tanzeum | Glaxo Smith Kline Llc | Injection, Powder, Lyophilized, for Solution | Subcutaneous | Drugs used in diabetes; alimentary tract and metabolism; blood glucose lowering drugs, excl. insulins. | Glucagon-like peptide 1 receptor |
| 1684 | Th1164 | Antithrombin Alfa | NA Full view | 0 | Ia | Hematological Disorders | Atryn | Gtc Biotherapeutics, Inc. | Injection, Powder, Lyophilized, for Solution | Intravenous | NA | NA |
| 1685 | Th1164 | Antithrombin Alfa | NA Full view | 0 | Ia | Hematological Disorders | Atryn | R Evo Bioloigics, Inc. | Injection, Powder, Lyophilized, for Solution | Intravenous | NA | NA |
| 1688 | Th1165 | Antithrombin III human | NA Full view | 0 | Ia | Hematological Disorders | Thrombate III | Grifols Therapeutics Inc | Powder for Solution | NA | NA | NA |
| 1691 | Th1165 | Antithrombin III human | NA Full view | 0 | Ia | Hematological Disorders | Thrombate III Pws IV 1000iu/vial | Miles Inc. Pharmaceutical Division | Powder for Solution | NA | NA | NA |
| 1708 | Th1170 | Blinatumomab | DIQLTQSPASLAVSLGQRAT Full view | 504 | IIIc | Cancer/Genetic | Blincyto | AMGEN | Lyophilized Powder for intravenous administration | Intravenous | Antineoplastic Agents, Immunosuppressive Agents, Monoclonal antibodies, Antineoplastic and Immunomodulating Agents | B-lymphocyte antigen CD19; T-cell surface glycoprotein CD3 delta chain |
| 1715 | Th1171 | C1 Esterase Inhibitor (Human) | NA Full view | 0 | Ia | Genetic Disorders | Berinert 1500 | Csl Behring Canada Inc | kit; Powder for Solution | Intravenous | NA | Plasma protease C1 inhibitor |
| 1717 | Th1171 | C1 Esterase Inhibitor (Human) | NA Full view | 0 | Ia | Genetic Disorders | Cinryze | Viropharma Biologics Inc | Powder for Solution | Intravenous | NA | Plasma protease C1 inhibitor |
| 1720 | Th1172 | Coagulation Factor XIII A-Subunit (Recombinant) | NA Full view | 0 | Ia | Hematological Disorders | Tretten | Novo Nordisk Canada Inc | Powder for Solution | Intravenous | NA | NA |
| 1722 | Th1173 | Conestat alfa | NA Full view | 0 | Ia | Genetic Disorders | Ruconest | Pharming; Santarus, Inc. | Powder for Solution | Intravenous | NA | NA |
| 1738 | Th1178 | Elotuzumab | heavy chain EVQLVESG Full view | 689 | IIIc | Cancer | NA | NA | Injection, Powder, Lyophilized, for Solution | Intravenous | NA | SLAM family member 7 |
| 1739 | Th1178 | Elotuzumab | heavy chain EVQLVESG Full view | 689 | IIIc | Cancer | Empliciti | E.R. Squibb & Sons, L.L.C. | Powder Lyophilized for Solution | Intravenous | NA | SLAM family member 8 |
| 1740 | Th1178 | Elotuzumab | heavy chain EVQLVESG Full view | 689 | IIIc | Cancer | Empliciti | E.R. Squibb & Sons, L.L.C. | Powder Lyophilized for Solution | Intravenous | NA | SLAM family member 9 |
| 1745 | Th1180 | Fibrinogen Concentrate (Human) | NA Full view | 0 | Ia | Genetic/Hematological | Riastap | Csl Behring Gmb H | Injection, Powder, Lyophilized, for Solution | Intravenous | NA | NA |
| 1788 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Carimune Nanofiltered | Csl Behring Ag | Injection, Powder, Lyophilized, for Solution | Intravenous | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
| 1797 | Th1191 | Vedolizumab | Heavy Chain Sequence Full view | 716 | IIa | Immunological Disorders | Entyvio | Takeda Pharmaceuticals America, Inc. | Injection, Powder, Lyophilized, for Solution | Intravenous | Immunosupressive agent, Antineoplastic agent | Integrin alpha-4, Integrin beta-7 |