Biomarker ID | 997 |
PMID | 23046102 |
Year | 2012 |
Biomarker | SOD2 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Blood |
Subjects | Humans |
Regulation | Upregulated in Metatstasis |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 2.5 |
Effect on Pathways | Pathways include: Cardiac protection against reactive oxygen species, IGF-1 receptor and longevity, Oxidative stress, Folate metabolism, ATM-dependent DNA damage response |
Experiment | Relpase Vs No Relapse |
Type of Biomarker | Prognostic |
Cohort | Study included 51 patients with distant relapse tumours, and 77 with no tumour relapse were included in the study. |
Senstivity | 51% |
Specificity | 70% |
AUC | 0.643 |
Accuracy | 63% |
Level Of Significance | p=0.01 |
Method Used | real-time reverse-transcriptase PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |