Biomarker ID | 996 |
PMID | 23046102 |
Year | 2012 |
Biomarker | GPX1 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Blood |
Subjects | Humans |
Regulation | Upregulated in Metatstasis |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 4.3 |
Effect on Pathways | Pathways inlcude: Cardiac protection against reactive oxygen species, Free radical-induced apoptosis, Arachidonic acid metabolism, Purine catabolism, Nucleotide metabolism |
Experiment | Relpase Vs No Relapse |
Type of Biomarker | Prognostic |
Cohort | Study included 51 patients with distant relapse tumours, and 77 with no tumour relapse were included in the study. |
Senstivity | 71% |
Specificity | 65% |
AUC | 0.755 |
Accuracy | 67% |
Level Of Significance | p<0.001 |
Method Used | real-time reverse-transcriptase PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |