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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID988
PMID23020913
Year2012
BiomarkerZinc α2-glycoprotein (ZAG)
Biomarker BasisExpression Based
BiomoleculeProtein
SourceUrine
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskOR: ZAG> 1.13: (6.88 (2.5–18.89)
Effect on PathwaysNA
ExperimentPCA VS No PCA group
Type of BiomarkerDiagnostic
CohortThe urine of 127 consecutive candidates for a transrectal ultrasound prostatic biopsy were selected for this study. Without cancer (n= 56), PIN (n= 29), Prostate Cancer (n= 42)
Senstivity78.6%
Specificity60%
AUC0.68 (95% CI 0.59–0.78)
AccuracyNA
Level Of Significancep=0.05
Method UsedImmunohistochemistry
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA