Biomarker ID | 988 |
PMID | 23020913 |
Year | 2012 |
Biomarker | Zinc α2-glycoprotein (ZAG) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Urine |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | OR: ZAG> 1.13: (6.88 (2.5–18.89) |
Effect on Pathways | NA |
Experiment | PCA VS No PCA group |
Type of Biomarker | Diagnostic |
Cohort | The urine of 127 consecutive candidates for a transrectal ultrasound prostatic biopsy were selected for this study. Without cancer (n= 56), PIN (n= 29), Prostate Cancer (n= 42) |
Senstivity | 78.6% |
Specificity | 60% |
AUC | 0.68 (95% CI 0.59–0.78) |
Accuracy | NA |
Level Of Significance | p=0.05 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |