Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 982 |
| PMID | 22977195 |
| Year | 2012 |
| Biomarker | EGFR |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Overexpressed for Progression Free Survival |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | Progression Free Survival |
| Type of Biomarker | Prognostic |
| Cohort | Patients with mCRPC progressing during or within 90 days after at least 12 weeks of docetaxel were included in this phase II trial. 29 patients were avaliable for IHC analysis. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p= 0.01 |
| Method Used | Immunohistochemistry |
| Clinical | Yes |
| Remarks | PFS was defined as the absence of disease progression for biochemical PSA progression |
| Clinical Trial Number | NCT00728663 |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |