Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 976 |
| PMID | 22935975 |
| Year | 2012 |
| Biomarker | RhoC score |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | 10-point increase in the RhoC score reduced the subsequent risk of PSA failure by about 6% |
| Odds Ratio/Hazard Ratio/Relative Risk | HR: 0.95 (95% CI: 0.91–0.99) |
| Effect on Pathways | NA |
| Experiment | Time to PSA Failure |
| Type of Biomarker | Prognostic |
| Cohort | 89 subjects were included in the study; 57 had a rising prostate specific antigen (PSA) post-operatively (‘cases’) and 32 did not (‘controls’). |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.009 |
| Method Used | Immunohistochemistry |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |