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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID964
PMID22866141
Year2011
BiomarkerSoluble interleukin-6 Receptor (sIL-6R)
Biomarker BasisConcentration Based
BiomoleculeProtein
SourceSerum
SubjectsHumans
RegulationUpregulated in higher Gleason Score (Without Gleason Score Upgrading: 65.62±23.87 Vs With Gleason Score Upgrading: 94.63±33.31)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysNA
ExperimentGleason Score Upgrading Vs No Gleason Score Uprading
Type of BiomarkerPrognostic
Cohort51 patients with Prostate cancer were selected such that 24 had GS (5-6), 22 had GS 7 and 5 had GS (8-10)
Senstivity80%
Specificity76%
AUC0.8
AccuracyNA
Level Of Significancep=0.024
Method UsedELISA
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA