Biomarker ID | 963 |
PMID | 22821756 |
Year | 2012 |
Biomarker | PCA3 + phi |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Urine + Serum |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | PCa Vs No-PCa |
Type of Biomarker | Diagnostic |
Cohort | 160 patients were included in the study, ouut of which 113 did not have prostate cancer and 47 had prostate cancer. |
Senstivity | 0.70 (95% CI: 0.57–0.83) |
Specificity | 0.76 (95% CI: 0.67–0.83) |
AUC | 0.77 (95% CI: 0.69–0.85) |
Accuracy | NA |
Level Of Significance | p=0.001 |
Method Used | NA |
Clinical | No |
Remarks | The PCA3 score was calculated as mRNA PCA3/mRNA PSA x 1000 |
Clinical Trial Number | NA |
Degree Of Validity | not validated on independent patient dataset |
Technical Name | NA |