Biomarker ID | 961 |
PMID | 22821756 |
Year | 2012 |
Biomarker | Prostate health index (phi) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa [No PCa: 36.84 (28.82–46.14) Vs PCa 49.97 (37.75–69.65)] |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | PCa Vs No-PCa |
Type of Biomarker | Diagnostic |
Cohort | 160 patients were included in the study, ouut of which 113 did not have prostate cancer and 47 had prostate cancer. |
Senstivity | 0.66 (95% CI: 0.51–0.7) |
Specificity | 0.72 (95% CI: 0.64–0.80) |
AUC | 0.66 (95% CI: 0.57–0.75) |
Accuracy | NA |
Level Of Significance | <0.001 |
Method Used | NA |
Clinical | No |
Remarks | Prostate health index (phi) = (p2PSA/fPSA x 100) |
Clinical Trial Number | NA |
Degree Of Validity | not validated on independent patient dataset |
Technical Name | NA |