Biomarker ID | 942 |
PMID | 22759231 |
Year | 2012 |
Biomarker | Mutation Status of KLK2 (Arg250Trp (rs198977)) |
Biomarker Basis | Mutation Based |
Biomolecule | Mutation |
Source | Blood |
Subjects | Humans |
Regulation | NA |
Odds Ratio/Hazard Ratio/Relative Risk | OR: Univariate Analysis: [1.69 (95% CI: 1.06–2.69)]; Multivariate Analysis: [2.04 (95% CI: 1.02–4.10)] |
Effect on Pathways | NA |
Experiment | Biochemical Recurrence Vs no Biochemical Recurrence (5 years) |
Type of Biomarker | Prognostic |
Cohort | 670 patients were selected for the study out of which 581 had no Biochemical Recurrence and 89 had |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | Univariate Analysis: p=0.025 ; Multivariate Analysis : p=0.044 |
Method Used | multiplex-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | KLK2 |